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1

Understanding the mechanism of IL-1β secretion

Gloria Lopez-Castejon, David Brough

Journal:

Cytokine & Growth Factor Reviews

Year:

2011

Language:

english

File:

PDF, 808 KB

english, 2011

2

Interleukin-1α expression precedes IL-1β after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues

Nadia M Luheshi, Krisztina J Kovács, Gloria Lopez-Castejon, David Brough, Adam Denes

Journal:

Journal of Neuroinflammation

Year:

2011

Language:

english

File:

PDF, 573 KB

english, 2011

3

Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease

Cocco, Mattia, Pellegrini, Carolina, Martínez-Banaclocha, Helios, Giorgis, Marta, Marini, Elisabetta, Costale, Annalisa, Miglio, Gianluca, Fornai, Matteo, Antonioli, Luca, López-Castejón, Gloria, Tapi

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.00 MB

english, 2017

4

The inflammasomes, Immune guardians at defence barriers

Palazon-Riquelme, Pablo, Lopez-Castejon, Gloria

Journal:

Year:

2018

Language:

english

File:

PDF, 737 KB

english, 2018

5

Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages

Nadia M. Luheshi, James A. Giles, Gloria Lopez-Castejon, David Brough

Journal:

European Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 431 KB

english, 2012

6

Novel macrophage polarization model: from gene expression to identification of new anti-inflammatory molecules

Gloria Lopez-Castejón, Alberto Baroja-Mazo, Pablo Pelegrín

Journal:

Cellular and Molecular Life Sciences

Year:

2011

Language:

english

File:

PDF, 970 KB

english, 2011

7

Nanoparticles can cause DNA damage across a cellular barrier

Bhabra, Gevdeep, Sood, Aman, Fisher, Brenton, Cartwright, Laura, Saunders, Margaret, Evans, William Howard, Surprenant, Annmarie, Lopez-Castejon, Gloria, Mann, Stephen, Davis, Sean A.

Journal:

Nature Nanotechnology

Year:

2009

Language:

english

File:

PDF, 548 KB

english, 2009

8

The colony-stimulating factor-1 receptor is a specific marker of macrophages from the bony fish gilthead seabream

Francisco J. Roca, Ma Pilar Sepulcre, Gloria López-Castejón, José Meseguer, Victoriano Mulero

Journal:

Molecular Immunology

Year:

2006

Language:

english

File:

PDF, 318 KB

english, 2006

9

Characterization of ATP-gated P2X7 receptors in fish provides new insights into the mechanism of release of the leaderless cytokine interleukin-1β

Gloria López-Castejón, Mark T. Young, José Meseguer, Annmarie Surprenant, Victoriano Mulero

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 1006 KB

english, 2007

10

The activation of gilthead seabream professional phagocytes by different PAMPs underlines the behavioural diversity of the main innate immune cells of bony fish

M. Pilar Sepulcre, Gloria López-Castejón, José Meseguer, Victoriano Mulero

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 584 KB

english, 2007

11

The type II interleukin-1 receptor (IL-1RII) of the bony fish gilthead seabream Sparus aurata is strongly induced after infection and tightly regulated at transcriptional and post-transcriptional levels

Gloria López-Castejón, M. Pilar Sepulcre, Francisco J. Roca, Barbara Castellana, Josep V. Planas, José Meseguer, Victoriano Mulero

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 1016 KB

english, 2007

12

Molecular and functional characterization of gilthead seabream Sparus aurata caspase-1: The first identification of an inflammatory caspase in fish

Gloria López-Castejón, M. Pilar Sepulcre, Iván Mulero, Pablo Pelegrín, José Meseguer, Victoriano Mulero

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 819 KB

english, 2008

13

Cell Volume Regulation Modulates NLRP3 Inflammasome Activation

Compan, Vincent, Baroja-Mazo, Alberto, López-Castejón, Gloria, Gomez, Ana I., Martínez, Carlos M., Angosto, Diego, Montero, María T., Herranz, Antonio S., Bazán, Eulalia, Reimers, Diana, Mulero, Victo

Journal:

Year:

2012

Language:

english

File:

PDF, 2.00 MB

english, 2012

14

Response to Boyle et al.

Angosto, Diego, López-Castejón, Gloria, Mulero, Victoriano, Pelegrín, Pablo

Journal:

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

15

Current status of inflammasome blockers as anti-inflammatory drugs

López-Castejón, Gloria, Pelegrín, Pablo

Journal:

Expert Opinion on Investigational Drugs

Year:

2012

Language:

english

File:

PDF, 529 KB

english, 2012

16

Microglia and macrophages differentially modulate cell death after brain injury caused by oxygen-glucose deprivation in organotypic brain slices

Girard, Sylvie, Brough, David, Lopez-Castejon, Gloria, Giles, James, Rothwell, Nancy J., Allan, Stuart M.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

17

Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing

Small, Ben G, McColl, Barry W, Allmendinger, Richard, Pahle, Jürgen, López-Castejón, Gloria, Rothwell, Nancy J, Knowles, Joshua, Mendes, Pedro, Brough, David, Kell, Douglas B

Journal:

Nature Chemical Biology

Year:

2011

Language:

english

File:

PDF, 1018 KB

english, 2011

18

NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury

Savage, Catherine Diane, Lopez-Castejon, Gloria, Denes, Adam, Brough, David

Journal:

Frontiers in Immunology

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

19

Tu1889 Targeting of NLRP3 Inflammasome With a Novel Selective Inhibitor as a Suitable Strategy for the Pharmacological Treatment of Bowel Inflammation

Pellegrini, Carolina, Fornai, Matteo, Colucci, Rocchina, Lopez-Castejon, Gloria, Cocco, Mattia, Garella, Davide, Bertinaria, Massimo, Blandizzi, Corrado, Antonioli, Luca

Journal:

Gastroenterology

Year:

2016

Language:

english

File:

PDF, 372 KB

english, 2016

20

P2X7 receptor-dependent tuning of gut epithelial responses to infection

Huang, Szu-Wei, Walker, Catherine, Pennock, Joanne, Else, Kathryn, Muller, Werner, Daniels, Michael J D, Pellegrini, Carolina, Brough, David, Lopez-Castejon, Gloria, Cruickshank, Sheena M

Journal:

Immunology & Cell Biology

Year:

2016

Language:

english

File:

PDF, 2.08 MB

english, 2016

21

Regulation of NLRP3 activation by the ubiquitin system

López-Castejón, Gloria

Journal:

Year:

2014

Language:

english

File:

PDF, 246 KB

english, 2014

22

Inhibition of Calpain Blocks the Phagosomal Escape of Listeria monocytogenes

Lopez-Castejon, Gloria, Corbett, David, Goldrick, Marie, Roberts, Ian S., Brough, David, Lenz, Laurel L.

Journal:

Year:

2012

Language:

english

File:

PDF, 541 KB

english, 2012

23

Deubiquitinases: Novel Therapeutic Targets in Immune Surveillance?

Lopez-Castejon, Gloria, Edelmann, Mariola J.

Journal:

Mediators of Inflammation

Year:

2016

Language:

english

File:

PDF, 1.47 MB

english, 2016

24

Canonical and Non-Canonical Activation of NLRP3 Inflammasome at the Crossroad between Immune Tolerance and Intestinal Inflammation

Pellegrini, Carolina, Antonioli, Luca, Lopez-Castejon, Gloria, Blandizzi, Corrado, Fornai, Matteo

Journal:

Frontiers in Immunology

Year:

2017

Language:

english

File:

PDF, 2.66 MB

english, 2017

25

Chloride regulates dynamic NLRP3-dependent ASC oligomerization and inflammasome priming

Green, Jack P., Yu, Shi, Martín-Sánchez, Fátima, Pelegrin, Pablo, Lopez-Castejon, Gloria, Lawrence, Catherine B., Brough, David

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.43 MB

english, 2018

26

Mechanisms of NLRP3 priming in inflammaging and age related diseases

Gritsenko, Anna, Green, Jack P., Brough, David, Lopez-Castejon, Gloria

Journal:

Cytokine & Growth Factor Reviews

Year:

2020

File:

PDF, 2.92 MB

2020

27

Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro

Gritsenko, Anna, Yu, Shi, Martin-Sanchez, Fatima, Diaz-del-Olmo, Ines, Nichols, Eva-Maria, Davis, Daniel M., Brough, David, Lopez-Castejon, Gloria

Journal:

Frontiers in Immunology

Year:

2020

File:

PDF, 2.17 MB

2020